Alström Syndrome touches multiple organ systems, and it’s not unusual for the eyes to be the first place trouble is spotted, sometimes long before other features of the syndrome are recognised. A useful comparison is Bardet-Biedl Syndrome, which is typically rod-led — Alström Syndrome tends to move the other way, unfolding as a cone-rod dystrophy where central vision and colour discrimination are among the first functions to be affected.
We approach Alström Syndrome with the understanding that it’s a systemic condition from the start, coordinating with whichever specialists are already overseeing its other effects on the body, while our own retinal assessment stays centred on the cone-rod pattern that separates this condition from other inherited dystrophies.
10+
years Experience
years Experience
5000+
Patients treated
Patients treated
100+
Countries served
Countries served
NABH
Guided facility
Guided facility
Ocular Symptoms
An early and pronounced sensitivity to light is something many families notice first, alongside the involuntary, rhythmic eye movements known as nystagmus, and a decline affecting both central and peripheral vision that usually starts in infancy or the first couple of years of life — earlier than what’s typical for most other inherited retinal conditions. Since central vision is caught up in the disease relatively early, patients often struggle with fine detail work and colour discrimination as part of the broader picture.
Underlying Causes
Alström Syndrome is caused by mutations in the ALMS1 gene, following an autosomal recessive pattern of inheritance. ALMS1 is important for cilia function throughout the body, and because the retina relies so heavily on that mechanism, it’s usually one of the tissues that shows measurable change earliest.
Diagnostic Evaluation
Our evaluation of the retina combines electroretinography, OCT imaging, and visual field testing, with careful attention paid to whether cone dysfunction on the ERG shows up ahead of, or together with, rod dysfunction — that pattern is what confirms a cone-rod rather than a rod-cone process. A positive ALMS1 finding on genetic testing supports the diagnosis and helps rule out other syndromic conditions that can look similar in their early stages.
Meet The Team
Our Eye Specialists
Dr. Pawan
Associate Professor, Vitreo-Retina Surgeon. 10+ Years Experience
Retinal disorders, diabetic retinopathy, and advanced retina procedures. Provides diagnostic evaluation and treatment planning for international patients.
Dr.Pallavee
Senior Consultant Ophthalmologist & Eye Surgeon· 26+ yrs experience
Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.
Dr. Robin
Consultant Ophthalmologist & Eye Surgeon, MD, DO .16+ Years Experience
Areas of Focus: Cataract surgery, corneal disorders, refractive procedures, and glaucoma management. Provides comprehensive eye care and surgical expertise for global patients.
Treatment Approach in India
Because visual symptoms in Alström Syndrome typically show up early, our retinal plan places priority on assessing eligible patients for stem cell therapy without unnecessary delay, alongside low-vision strategies appropriate for a young child, all aligned with whatever care the family already has for the syndrome’s other systemic aspects.
Reviews
What Our Patients Say
DR NAAGALAKSHMI R
1 week ago
Asha Babbar
2 weeks ago
The overall experience at the RP Treatment Center was very good. The staff was supportive and caring, and we provided proper attention and guidance during treatment. The environment at the center was clean and comfortable. The doctors and staff tried to understand patients' needs and explained the treatment process well.
Overall, I am satisfied with the service and care. Highly recommended!
Overall, I am satisfied with the service and care. Highly recommended!
Harshita Kapoor
2 weeks ago
Life‑Changing Experience with RP Therapy”
After years of struggling with vision loss due to Retinitis Pigmentosa, I finally found hope here. The doctors were highly professional, explained the stem cell treatment in detail, and gave me confidence at every step. The therapy was smooth, and I’ve already noticed positive changes in my daily life. Their dedication, care, and advanced medical approach make this center truly trustworthy
After years of struggling with vision loss due to Retinitis Pigmentosa, I finally found hope here. The doctors were highly professional, explained the stem cell treatment in detail, and gave me confidence at every step. The therapy was smooth, and I’ve already noticed positive changes in my daily life. Their dedication, care, and advanced medical approach make this center truly trustworthy
Yash Chauhan
2 weeks ago
I had a really good experience at RP Treatment Centre. The doctor listened to my problem patiently and explained the treatment in a simple way. The staff was polite and the clinic was clean. I started feeling better after the treatment. Highly recommended!
pragya chauhan
2 weeks ago
Very satisfied with the service. The doctor is experienced and gives proper attention to every patient. The staff is friendly, and the overall environment is comfortable. Thank you, RP Treatment Centre, for the excellent care.
Manisha kapoor
2 weeks ago
I had been struggling with Retinitis Pigmentosa for years, and finding this center was truly life‑changing. The doctors provided a thorough medical evaluation and explained every step of the stem cell therapy process with clarity. The treatment was smooth, professional, and I noticed encouraging improvements in my vision within weeks. Their continuous follow‑up care and compassionate support made me feel confident throughout the journey. Highly recommended for anyone seeking advanced RP treatment in India.
Frequently Asked Questions
Why is my child losing central vision sooner than what I’ve read about with other retinal conditions?
“That’s characteristic of Alström Syndrome specifically — it tends to follow a cone-rod pattern, so central and colour vision are affected relatively early, unlike the rod-first course seen in classic RP
”
What’s the actual difference between Alström Syndrome and Bardet-Biedl Syndrome? Some symptoms seem to overlap.
”
They’re caused by different genes and follow different retinal patterns, even though some systemic features overlap — Alström typically affects central vision earlier through a cone-rod process, while Bardet-Biedl generally follows the rod-first pattern seen in classic RP. Genetic testing distinguishes between them.”
With multiple organs affected, what else should our family keep watch on?
“Alström Syndrome can involve hearing, heart function, and metabolic health, so it’s worth maintaining coordination with whichever specialists are managing those areas, alongside the retinal care we provide.”
Is there an age below which we shouldn’t bother assessing a child for Alström Syndrome?
“No such cutoff exists. Given how early visual symptoms tend to appear in this condition, getting a baseline assessment done sooner gives us a solid reference point for tracking any future change.”
